2022
Hippocampal representations of foraging trajectories depend upon spatial context
Nature Neuroscience
in press
2022
Motor cortical output for skilled forelimb movement is selectively distributed across projection neuron classes
Science Advances
10.1126/sciadv.abj5167
2021
Dissociable contributions of phasic dopamine activity to reward and prediction
Cell Reports
10.1016/j.celrep.2021.109684
2021
Neuron-type specificity of dorsal raphe projections to ventral tegmental area
biorxiv
10.1101/2021.01.06.425641
2020
Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings
Science
372(6539)
2020
Basal ganglia circuits for action specification
Annual Reviews
10.1146/annurev-neuro-070918-050452
2019
Learning from action: reconsidering movement signaling in midbrain dopamine neuron activity
Neuron
104(1): 63-77
2019
A repeated molecular architecture across thalamic pathways
Nature Neuroscience
10.1038/s41593-019-0483-3
2019
Reconstruction of 1,000 projection neurons Reveals New Cell Types and Organization of Long-Range connectivity in the mouse brain
Cell
179(1): 268-81
2019
High-Throughput Synapse-Resolving Two-Photon Fluorescence Microendoscopy ... In Vivo
eLife
8:e40805
2018
Expansion of the Optogenetics Toolkit through Topological Inversion of Rhodopsins
Cell
175(4):1131-1140
2018
The timing of action determines reward expectation signals in dopamine neurons
Nature Neuroscience
21(11):1563-1573
2018
A proposed circuit computation in basal ganglia: history dependent gain
Movement Disorders
33(5):704-16
2016
Opponent and bidirectional control of movement velocity in the basal ganglia
Nature
533(7603):402-6
2016
The basal ganglia: from motor commands to the control of vigor
Current Opinion in neurobiology
37:158-166
2015
A minimally invasive microendoscopy system for in vivo functional imaging
Biomedical Optics Express
6(11): 4546-56
2015
Dopamine is required for the neural representation and control of movement vigor
Cell
162(6): 1418-30
2015
A specific component of the evoked potential mirrors phasic dopamine neuron activity during conditioning
Journal of Neuroscience
35(29): 10451-10459
Midbrain dopamine (DA) neurons receive diverse inputs from regions distributed throughout the neuraxis from frontal neocortex to the mesencephalon. Here we use local field potentials recorded from the midbrain to show that the evoked potential (mEP) faithfully reflects the temporal and spatial structure of the phasic response of midbrain neuron populations during classical conditioning.
2014
The inhibitory microcircuit of the substantia nigra provides feedback gain control
eLIFE
3:e02397
Dysfunction of the basal ganglia produces severe deficits in the timing, initiation, and vigor of movement. These diverse impairments suggest a control system gone awry. In engineered systems feedback is critical for stable control. Here we show that one feedback pathway, axon collaterals of substantia nigra projection neurons, control the gain of the basal ganglia output. The importance of feedback for engineered control systems implies that the intranigral microcircuit could be essential to normal basal ganglia function.
2014
Precise spatial coding is preserved along the longitudinal hippocampal axis
Hippocampus
24(12):1533-48
2013
RIVETS: a 3D printable system for in vivo and in vitro electrophysiology and imaging
PLoS ONE
9(2): e89007
2013
Neural signals of extinction in the inhibitory microcircuit of the ventral midbrain
Nature Neuroscience
16(1):71-8
2010
Inputs to the dorsal striatum of the mouse conserve the parallel circuit architecture of the forebrain
Frontiers in Neuroanatomy
4:147
2009
Stochastically gating ion channels enable patterned spike firing through activity-dependent modulation of spike probability