neural circuits. learning. computation.

flexible actions

Behavioral and neural changes underlying skilled motor actions

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models of learning

Computations and circuit mechanisms of reinforcement learning

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tools + neuroscience

Molecular reagents, hardware, and software for systems neuroscience

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New preprint

Luke's new manuscript, Mesolimbic dopamine adapts the rate of learning from errors in performance, has been posted to biorxiv.

read online


Luke gave a seminar A role for dopamine in value-free learning as part of Neuromodulation in the brain block of seminars in WWNeuRise.

watch online


Our summer student, Meyerhoff Scholar Lana Jones, returns to UNC for her Senior year of undergrad. Lana, working with Luke, helped us start an exciting project on deep brain stimulation.

read about the Meyerhoff program

New paper

Weixing's new paper, Dissociable contributions of phasic dopamine activity to reward and prediction, is now available in its final formatted version at Cell Reports.

read online


Josh will again be helping to run the newest installment of our Junior Scientist Workshop for Mechanistic Cognitive Neuroscience October 24-29. We are alooking forward to virtually hosting ~20 students from around the world.

workshop info


Josh is presenting at Basel, SFN, Duke, etc this Fall. We will post details about availability of these virtual seminars as they become available.

We are part of the Mechanistic Cognitive Neuroscience research area - A multi-lab team of tool-builders, biologists, and theorists.

We are a collection of scientists with a broad range of backgrounds from biophysics to psychology.

Our lab has a set of shared values that articulate our commitment to disseminate our work, embrace diversity, and engage future scientists through outreach.

Over the past few years we have focused on studying the circuits and computations of the cerebral cortex and basal ganglia in the context of reward seeking behaviors in mice. Previous work has spanned a range of questions from behavioral measures of disease progression in human patients to the structure glutamate receptors.

  View all of our publications
  Data from Google Scholar

Work with us

Our lab spans a wide range of approaches from electrophysiology during behavior to two-photon imaging. We are always on the lookout to work with talented, interested people with diverse skills and backgrounds either as members of the lab or as visiting scientists through the Janelia Visiting Scientists program.

We also keenly interested to help expose students to neuroscience research and help launch research careers through our participation in the Janelia Graduate Program or the Graduate Research Fellowship program. For undergraduates, our lab is a regular participant in the Janelia Undergraduate Scholars program.

All inquiries can be sent directly to the lab using the form below.

Or just listen to what we are listening to...